Fallout 4

macOS Compatibility

Compatibility layer	Rating	Notes
CrossOver	Playable	Some graphical issues, playable framerate.^[1] Requires fixes, see #CrossOver.
Wine	Playable	The game runs at an acceptable frame rate. Some lighting issues.^[2]^[3]
Virtualization
Parallels	Playable	Graphics settings must be set to Ultra, played in windowed mode.^[4] Won't load.^[5]. Cracked version framerate is low.^[6]

See PCGamingWiki for Windows and/or Linux availability.

VATS isn't working correctly: chances to hit near 0% or 1% most of the time.
Various render glitches: mostly seen in vegetation and plants represented in the game and also broken light effects. These render glitches are not preventing the game to be played fully though, they're just annoying glitches here and there. (Jun 2023: transparency issue was fixed in the latest Crossover / Wineskin versions)
Prone to crash: often times, audio will start to fail progressively after running the game for a while. first NPC talks connot be heard anymore, then other audio problem will follow thus rendering some areas of the game impossible to pass through. Fix is easy enough: quit and relaunch the game.

CrossOver Bottle settings^[1]
Click Bottles icon `Ctrl` + click Bottle Enable Settings - Enable Performance Enhanced Synchronization (ESync) Enable Settings - Enable DXVK Backend D3D11

Wine configuration Library overrides^[1]
Under Control Panels, double click Wine Configuration In Libraries select 'New override for library' Select each library file and click 'Add' x3audio1_6 x3audio1_7 xaudio2_6 xaudio2_7

Add bBackgroundMouse=1 to Fallout4.ini^[1]
Find `Fallout4.ini` normally within `\Documents\My Games\Fallout4.ini` `Ctrl` + click `Fallout4.ini` and open with TextEdit Under the [Controls] heading add the line `bBackgroundMouse=1` Click File and Save